gastric acid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17030	Tegoprazan		ATPase , Proton pump
	Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5...		ATPase , Proton pump
T38612	Linaprazan glurate		Others
	Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases.		Others
T4579	Pentagastrin	ICI-50123	Others , cholecystokinin
	Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins.		Others , cholecystokinin
T4981	Anisotropine Methylbromide		Prostaglandin Receptor , AChR
	Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.		Prostaglandin Receptor , AChR
T22724	Dimaprit dihydrochloride		NOS , NO Synthase , Histamine Receptor
	Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion.		NOS , NO Synthase , Histamine Receptor
T0498	Salsalate	Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171	Reactive Oxygen Species , COX
	Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.		Reactive Oxygen Species , COX
T0686	Orlistat	Ro-18-0647,Tetrahydrolipstatin	Apoptosis , Others , Fatty Acid Synthase
	Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor.		Apoptosis , Others , Fatty Acid Synthase
T6700	Tenatoprazole	TU-199	Proton pump
	Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).		Proton pump
T8599	Betazole dihydrochloride	Betazole hydrochloride	Histamine Receptor
	Betazole dihydrochloride (Betazole hydrochloride) is an agonist of H2 receptor.		Histamine Receptor
T1756L	Ilaprazole	IY81149,IY 81149,IY-81149	Proton pump , TOPK
	Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm...		Proton pump , TOPK
T1756	Ilaprazole sodium	IY-81149 sodium	Proton pump , TOPK
	Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...		Proton pump , TOPK
T0674	Lansoprazole	A-65006,AG-1749	Proton pump , Phospholipase , Antibacterial
	Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo...		Proton pump , Phospholipase , Antibacterial
T8388	Vonoprazan	TAK-438 (free base)	Proton pump
	Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis		Proton pump
T21254	Vonoprazan Fumarate	TAK-438,TAK 438,Vonoprazan Fumurate,TAK438	Proton pump
	Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...		Proton pump
T7615	Xenopsin	Xenopsin(2TFA)	Others
	Xenopsin (Xenopsin(2TFA))(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin.		Others
T1627	Famotidine	MK-208	Histamine Receptor
	Famotidine (MK-208) is a propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidi...		Histamine Receptor
T15005	CP-66948		Histamine Receptor
	CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa.		Histamine Receptor
T13145	Thiazolidinone-Derivatives-1		Others
	Thiazolidinone-Derivatives-1 inhibits the secretion of gastric acid and can be used in research on the treatment of gastric and duodenal ulcers.		Others
TP1309	Gastric mucin		Antibacterial , Antibiotic
	Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.		Antibacterial , Antibiotic
T10221	Abeprazan hydrochloride	DWP14012 hydrochloride,Fexuprazan hydrochloride	Proton pump
	Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat...		Proton pump